DNA
From Wikipedia, the free encyclopedia
For a non-technical introduction to the topic, see
Introduction to genetics.
For other uses, see
DNA (disambiguation).
The structure of part of a DNA
double helixDeoxyribonucleic acid (DNA) is a
nucleic acid that contains the
genetic instructions used in the development and functioning of all known living
organisms and some
viruses. The main role of DNA
molecules is the long-term storage of
information. DNA is often compared to a set of
blueprints or a recipe, or a
code, since it contains the instructions needed to construct other components of
cells, such as
proteins and
RNA molecules. The DNA segments that carry this genetic information are called
genes, but other DNA sequences have structural purposes, or are involved in regulating the use of this genetic information.
Chemically, DNA consists of two long
polymers of simple units called
nucleotides, with
backbones made of
sugars and
phosphate groups joined by
ester bonds. These two strands run in opposite directions to each other and are therefore
anti-parallel. Attached to each sugar is one of four types of molecules called
bases. It is the sequence of these four bases along the backbone that encodes information. This information is read using the
genetic code, which specifies the sequence of the
amino acids within proteins. The code is read by copying stretches of DNA into the related nucleic acid RNA, in a process called
transcription.
Within cells, DNA is organized into X-shaped structures called
chromosomes. These chromosomes are duplicated before cells
divide, in a process called
DNA replication.
Eukaryotic organisms (
animals,
plants,
fungi, and
protists) store most of their DNA inside the
cell nucleus and some of their DNA in the
mitochondria (animals and plants) and
chloroplasts (plants only)
[1].
Prokaryotes (
bacteria and
archaea) however, store their DNA in the cell's
cytoplasm. Within the chromosomes,
chromatin proteins such as
histones compact and organize DNA. These compact structures guide the interactions between DNA and other proteins, helping control which parts of the DNA are transcribed.